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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRCA1 All Species: 13.64
Human Site: S616 Identified Species: 60
UniProt: P38398 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P38398 NP_009225.1 1863 207721 S616 N R L R R K S S T R H I H A L
Chimpanzee Pan troglodytes Q9GKK8 1863 207881 S616 N R L R R K S S T R H I H A L
Rhesus Macaque Macaca mulatta Q6J6I9 1863 207771 S615 N R L R R K S S T R H I H A L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P48754 1812 198651 S610 N R L R R K S S I R C A L P L
Rat Rattus norvegicus O54952 1817 199849 K599 E L N V H S S K A P K K N R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989500 1749 193920 S562 K E K C D E N S A V K E N P L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 93 N.A. N.A. 55.4 56.3 N.A. N.A. 32.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 95.9 N.A. N.A. 69.4 70.2 N.A. N.A. 49.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 66.6 13.3 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 66.6 20 N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 34 0 0 17 0 50 0 % A
% Cys: 0 0 0 17 0 0 0 0 0 0 17 0 0 0 0 % C
% Asp: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 17 0 0 0 17 0 0 0 0 0 17 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 17 0 0 0 0 0 50 0 50 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 0 50 0 0 0 % I
% Lys: 17 0 17 0 0 67 0 17 0 0 34 17 0 0 0 % K
% Leu: 0 17 67 0 0 0 0 0 0 0 0 0 17 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 67 0 17 0 0 0 17 0 0 0 0 0 34 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 17 0 0 0 34 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 67 0 67 67 0 0 0 0 67 0 0 0 17 0 % R
% Ser: 0 0 0 0 0 17 84 84 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % T
% Val: 0 0 0 17 0 0 0 0 0 17 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _